I'd have to say that my favorite is Bill Burr. He has probably made me laugh my ass off more than anyone else. I can watch his standup specials on Netflix over and over and still laugh hard. His style of delivery and "attack" is unequaled IMHO.
Here's the classic act about plastic surgery:
Another one of my favorite acts was from "I'm Sorry You Feel That Way" on Netflix. The part about the population problem.